Clipmarks | Glucose metabolism Clips

Top Ten Spices That Defend You Against Aging

Sat, 23 Aug 2008 07:48:13 GMT

clipped by: mugofcoffee

Herbs and spices are rich in antioxidants, and they are also potent inhibitors of tissue damage and inflammation caused by high levels of blood sugar.

When researchers tested extracts from 24 common herbs and spices, they found a direct correlation between antioxidant phenol content and the ability of the extracts to block the formation of compounds that contribute to damage caused by diabetes and aging.

Cloves (ground)

Cinnamon (ground)

Jamaican allspice (ground)

Apple pie spice (mixture)

Oregano (ground)

Pumpkin pie spice (mixture)

Marjoram

Sage

Thyme

Gourmet Italian spice

This is not the first time scientists have declared culinary herbs and spices as potent anti-diabetic alternatives.

Cinnamon and cinnamon extracts have previously been shown to effectively lower blood sugar. As a matter of fact, cinnamon was found to increase glucose metabolism 20-fold, in one such study!

1 in 4 Americans Now Suffer From Pre-Diabetes or Some Form of Diabetes

Exercise in a Pill

Thu, 31 Jul 2008 22:50:38 GMT

clipped by: Silkweaver
clipper's remarks: Previous work with genetically engineered mice in the Evans lab had revealed that permanently activating a genetic switch known as PPAR delta turned mice into indefatigable marathon runners. In addition to their super-endurance, the altered mice were resistant to weight gain, even when fed a high-fat diet that caused obesity in ordinary mice. On top of their lean and mean physique, their response to insulin improved, lowering levels of circulating glucose.

Clip Source: www.physorg.com

Trying to reap the health benefits of exercise?

Forget treadmills and spin classes, researchers at the Salk Institute for Biological Studies may have found a way around the sweat and pain.

They identified two signaling pathways that are activated in response to exercise and converge to dramatically increase endurance.

The team of scientists, led by Howard Hughes Medical Investigator Ronald M. Evans, Ph.D., a professor in the Salk Institute's Gene Expression Laboratory report in the July 31 advance online edition of the journal Cell that simultaneously triggering both pathways with oral drugs turned laboratory mice into long-distance runners and conferred many of exercise's other benefits.

The researchers fed untrained mice AICAR, a synthetic AMP analog that directly activates AMPK. After only four weeks and without any prior training, these mice got up and ran 44 percent longer than untreated, untrained mice. "That's as much improvement as we get with regular exercise," says Narkar.

Tags: metabolism, exercise, physiology

how being overweight causes diabetes type2

Thu, 24 Jul 2008 22:50:53 GMT

clipped by: akinzo2

Clip Source: www.doctors.net.uk

Obesity is accompanied by an elevated fasting level of plasma insulin and an exaggerated insulin response to an oral glucose load. Overall fatness and the distribution of body fat influence the metabolism of glucose through independent but additive mechanisms. Increasing upper body obesity is accompanied by a progressive increase in the response of glucose and insulin to an oral glucose challenge, and there is a positive correlation between increasing upper body obesity and resistance to the effects of insulin. Posthepatic insulin delivery is increased in upper body obesity, leading to more marked peripheral insulin concentrations which, in turn, lead to peripheral resistance to insulin.

Obesity and type 2 diabetes mellitus

Anaerobic Exercise

Wed, 02 Jul 2008 16:37:28 GMT

clipped by: SenorCoconut

Clip Source: en.wikipedia.org

Anaerobic exercise is exercise intense enough to trigger anaerobic metabolism. It is used by athletes in non-endurance sports to build power and by body builders to build muscle mass. Muscles trained under anaerobic conditions develop differently, leading to greater performance in short duration, high intensity activities, which last up to about 2 minutes.^[1]

Aerobic exercise, on the other hand, includes lower intensity activities performed for longer periods of time. Such activities like walking, running, swimming, and cycling require a great deal of oxygen to generate the energy needed for prolonged exercise to keep you at a certain energy level.

There are two types of anaerobic energy systems, the ATP-CP energy system, which uses creatine phosphate as the main energy source, and the lactic acid (or anaerobic glycolysis) system that uses glucose (or glycogen) in the absence of oxygen.

Tags: anaerobic exercise

Neuroscientists Show Insulin Receptor Signaling Regulates Structure Of Brain Circuits

Tue, 24 Jun 2008 08:57:24 GMT

clipped by: tabsey
clipper's remarks: Could lead to lots of places, but if it can help with alzheimer's disease that would be a great start.

Clip Source: www.sciencedaily.com

ScienceDaily (June 23, 2008) — A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated for the first time in living animals that insulin receptors in the brain can initiate signaling that regulates both the structure and function of neural circuits.

The finding suggests a significant role for this class of receptors and perhaps for insulin, not only in brain development, but also in cognition and in pathological processes in which cognition is impaired, as in Alzheimer’s disease, for example.

Insulin receptors on the surface of cells throughout the body have long been understood to play a central role in controlling metabolism through the regulation of glucose. When a molecule of insulin, a hormone, “docks” with the receptor, a complex signaling cascade is set in motion inside a cell, culminating in the cell’s uptake of insulin.

The Brain Is Not “Insulin-Insensitive” After All

Tags: medicine

The Health Benefits Of Green Tea

Sat, 14 Jun 2008 12:30:53 GMT

clipped by: SenorCoconut

Clip Source: www.elements4health.com

Diabetes.
Consumption of green tea has been associated with a reduced risk for type 2 diabetes, and people who drink green tea regularly are less likely to develop diabetes. The results of a study published in the August 2004 issue of BMC Pharmacology, stated that green tea promoted glucose metabolism in the healthy human participants, providing evidence that green tea has an anti-diabetic effect.

Skin.
It has been suggested that a polyphenolic fraction from green tea may prevent UV radiation-induced skin cancer. There is however insufficient scientific research to back this theory up, and further studies are needed. In a double blind trial of green tea extracts in its role to treat aging skin, participants treated with a combination regimen of topical and oral green tea showed improvement in elastic tissue content.

Tooth Decay.
Several studies have demonstrated the anti-bacterial properties of green tea polyphenols are an effective agent against tooth decay.

Tags: green tea, egcg, weight loss, antioxidant, arthritis, diabetes, cancer, thermogenic, cholesterol

Not all fat created equal

Wed, 07 May 2008 09:25:24 GMT

clipped by: wildcat

Clip Source: physorg.com

It has long been known that type 2 diabetes is linked to obesity, particularly fat inside the belly. Now, researchers at the Joslin Diabetes Center have found that fat from other areas of the body can actually reduce insulin resistance and improve insulin sensitivity.

In a study published in the May issue of Cell Metabolism, a team lead by C. Ronald Kahn, M.D. found that subcutaneous fat -- fat found below the skin, usually in the hips and thighs -- is associated with reduced insulin levels and improved insulin sensitivity.

“This points to a new opportunity to find substances made by subcutaneous fat that may actually be good for glucose metabolism,’’ said Dr. Kahn, Head of the Joslin Research Section on Obesity and Hormone Action and the Mary K. Iacocca Professor of Medicine at Harvard Medical School. “If we can identify how subcutaneous fat does this, we will have a big clue as to where to look for these substances.”

Tags: fat, diabetes, glucose metabolism

Grape Skin Compound Fights The Complications Of Diabetes

Thu, 20 Mar 2008 15:22:43 GMT

clipped by: tabsey
clipper's remarks: Hope this one works. Will be the treatment for the sugar hangover - which I've found to be worse with fats than sugar.

Clip Source: www.sciencedaily.com

ScienceDaily (Mar. 20, 2008) — Research carried out by scientists at the Peninsula Medical School in the South West of England has found that resveratrol, a compound present naturally in grape skin, can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes, according to a recently published paper in the science journal "Diabetes, Obesity and Metabolism."

The elevated levels of glucose that circulate in the blood of patients with diabetes causes micro- and macrovascular complications by damaging mitochondria, the tiny power plants within cells responsible for generating energy. When they are damaged they can leak electrons and make highly damaging 'free radicals'.

Complications that can result when this happen include nephropathy (kidney disease), heart disease and retinopathy (which if left untreated can lead to blindness).

Tags: medical

Chinese Green Tea

Fri, 22 Feb 2008 15:03:11 GMT

clipped by: rob24hrs
clipper's remarks: Have you tasted Chinese green tea? As you all know, green tea is the most popular types of Chinese tea. Many people, not only Chinese, consider it as the best drink for sultry summers. The main reason for this claim is the fact that green tea is cool and fights off inflammation. Many have even claimed that it relieves fever.

Clip Source: www.squidoo.com

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Tags: green tea, chines green tea, cha

The Human Cell - Complete metabolic pathways

Mon, 10 Dec 2007 17:58:50 GMT

clipped by: Nullo

Clip Source: madsenblog.dk

Complete metabolic pathway

Mind-blowing isn’t it?!

Think about it…even the most stupid son of an b**** you’ve ever met…his cells are still capable of performing 99% of these intricate biosynthesis’s and breakdowns. For me the number is somewhere around 98.99%…I’m lactose intolerant, which means I lack the enzyme lactase…the enzyme that cleaves lactose into glucose and galactose. Give me a glass of milk and I turn into a highly deadly biochemical weapon

Tags: science, biochemistry, metabolism, catabolism

birth weight and size determine adult health

Fri, 16 Nov 2007 03:48:10 GMT

clipped by: sylviadafox
clipper's remarks: "A study published last year by Dr. Barker and his colleagues hinted of a possible link between intrauterine hormonal or nutritional factors and the risk of developing ovarian cancer. Noting that there is an association between ovarian cancer and tallness, the researchers examined early growth in 5,585 women in Hertfordshire.

Although there was no difference in average birth weights, the 41 women who died from ovarian cancer ''had had a high rate of weight gain in infancy,'' weighing nearly a pound more on average at their first birthday than women free of this cancer. The researchers suggested that hormonal patterns that affected the ovary might be established in utero and result in speeded growth in infancy, early menarche and an increased risk of infertility and ovarian cancer later in life. "

Clip Source: query.nytimes.com

More than two dozen studies of people in several countries

have suggested that what and how much a mother eats during pregnancy can ''program'' a child's organ systems before birth and set the stage for metabolic or hormonal changes that may result in disease many decades later.

Dr. David J. P. Barker, an epidemiologist who

is the leading proponent of the hypothesis that maternal nutrition can influence adult disease.

statistically the relationship of size at birth to later medical problems is clear. These studies show that small size, meaning under 5.5 pounds, can result in a 35 percent higher rate of coronary deaths in later life and a sixfold increase in the risk of diabetes or impaired glucose metabolism.

Heart disease is one of the clearest results of poor maternal nutrition.

Even more disturbing is the fact that in animal studies nutritional improvement after birth cannot erase intrauterine deprivation that raises the risk of adult disease.

Tags: health

In Diabetes, A Complex Of Causes

Wed, 17 Oct 2007 12:53:46 GMT

clipped by: debbyski

Clip Source: www.nytimes.com

An explosion of new research is vastly changing scientists’ understanding of diabetes and giving new clues about how to attack it.

New research suggests that a hormone from the skeleton, of all places, may influence how the body handles sugar. Mounting evidence also demonstrates that signals from the immune system, the brain and the gut play critical roles in controlling glucose and lipid metabolism. (The findings are mainly relevant to Type 2 diabetes, the more common kind, which comes on in adulthood.)

The defining feature of diabetes is elevated blood sugar. But the reasons for abnormal sugar seem to “differ tremendously from person to person,” said Dr. Robert A. Rizza, a professor at the Mayo Clinic College of Medicine. Understanding exactly what signals are involved, he said, raises the hope of “providing the right care for each person each day, rather than giving everyone the same drug.”

Tags: wow, everyone, is, not, the, same

High-Fructose Corn Syrup May Act More Like Fat Than Sugar in the Body

Mon, 15 Oct 2007 20:53:50 GMT

clipped by: melizer
clipper's remarks: This was in 2003. Any follow up studies?

Clip Source: www.washingtonpost.com

Sweet but Not So Innocent?

High-Fructose Corn Syrup May Act More Like Fat Than Sugar in the Body

In 1966, refined sugar, also known as sucrose, held the No. 1 slot, accounting for 86 percent of sweeteners used, according to the USDA. Today, sweeteners made from corn are the leader, racking up $4.5 billion in annual sales and accounting for 55 percent of the sweetener market. That switch largely reflects the steady growth of high-fructose corn syrup, which climbed from zero consumption in 1966 to 62.6 pounds per person in 2001.

Made from corn starch, high-fructose corn syrup is a thick liquid that contains two basic sugar building blocks, fructose and glucose, in roughly equal amounts. Sucrose, most familiar to consumers as table sugar, is a larger sugar molecule that breaks down into glucose and fructose in the intestine during metabolism.

"Fructose is absorbed differently" than other sugars, says Bray. "It doesn't register in the body metabolically the same way that glucose does."

Tags: sugar, corn syrup, weight loss

Green Tea Health

Sat, 22 Sep 2007 06:04:35 GMT

clipped by: greenteafreak
clipper's remarks: A good article on green tea health benefits

Clip Source: www.squidoo.com

-Green tea can slightly speed up metabolism, and help with the breakdown of glucose. So it's a great after-meal drink... get those glucose molecules broken down faster.

If you want a little bit of a more in-depth overview of green tea (or black for that matter), you can check out this site that I found informative...

Coffee has become the drink of America; it is a social phenomenon that has permeated the states completely. The question is, is it a healthy phenomenon? That's a good question. If you're somewhat into health foods and such, or even if you're not, you've probably heard something about the health benefits of green tea. So what's better, coffee or green tea?

So which is better? In the end, it comes down to personal discretion. Green tea health benefits, at least at this point, have shown themselves superior, but those of coffee are not something to sneeze at either.

Tags: green, tea, health, benefits

Clipmarks | Glucose metabolism Clips

Top Ten Spices That Defend You Against Aging

Exercise in a Pill

how being overweight causes diabetes type2

Anaerobic Exercise

Neuroscientists Show Insulin Receptor Signaling Regulates Structure Of Brain Circuits

The Health Benefits Of Green Tea

Not all fat created equal

Grape Skin Compound Fights The Complications Of Diabetes

Chinese Green Tea

The Human Cell - Complete metabolic pathways

Complete metabolic pathway

birth weight and size determine adult health

More Evidence for Links between Diabetes and Sleep Disorders

In Diabetes, A Complex Of Causes

High-Fructose Corn Syrup May Act More Like Fat Than Sugar in the Body

Sweet but Not So Innocent?

High-Fructose Corn Syrup May Act More Like Fat Than Sugar in the Body

Green Tea Health

Chinese Green Tea